Publications

* Equal Contribution, # corresponding author

Google Scholar: https://scholar.google.com/citations?user=flPaAgUAAAAJ&hl=en&oi=ao

19. Jalihal AP*, Pitchiaya S*#, Xiao L, Bawa P, Jiang X, Bedi K, Cieslik M, Ljungman M, Chinnaiyan AM# and Walter NG#, Multivalent proteins rapidly and reversibly phase-separate upon osmotic cell volume change. bioRxiv (2019).

18. Pitchiaya S#, Mourao MDA, Jalihal AP, Xiao L, Jiang X, Chinnaiyan AM, Schnell S and Walter NG#, Dynamic recruitment of single RNAs to processing bodies depends on RNA functionality. Molecular Cell (2019), 74:521. Featured in Chowdhury et al., Molecular Cell, 2019 (Perspectives)

17. Parolia A*, Cieslik M*, Chu SC, Xiao L, Ouchi T, Zhang Y, Wang X, Vats P, Cao X, Pitchiaya S, Su F, Wang R, Feng FY, Wu YM, Lonigro RJ, Robinson DR and Chinnaiyan AM#. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature (2019), 571:413. Featured in Stone L, Nature Reviews Urology, 2019 (In Brief)

16. Zhang Y*, Pitchiaya S*, Cieslik M*, Niknafs YS, Tien JC, Hosono Y, Iyer MK, Yazdani S, Subramaniam S, Shukla SK, Jiang X, Wang L, Liu TY, Uhl M, Gawronski AR, Qiao Y, Xiao L, Dhanasekaran SM, Juckette KM, Kunju LP, Cao X, Patel U, Batish M, Shukla GC, Paulsen MT, Ljungman M, Jiang H, Mehra R, Backofen R, Sahinalp CS, Freier SM, Watt AT, Guo S, Wei JT, Feng FY, Malik R and Chinnaiyan AM#, Analysis of the androgen receptor–regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression, Nature Genetics (2018), 50:814

15. Hosono Y*, Niknafs YS*, Prensner JR, Iyer MK, Dhanasekaran SM, Mehra R, Pitchiaya S, Tien J, Escara-Wilke J, Poliakov A, Chu SC, Saleh S, Sankar K, Su F, Guo S, Qiao Y, Freier SM, Bui HH, Cao X, Malik R, Johnson TM, Beer DG, Feng FY, Zhou W and Chinnaiyan AM#, Oncogenic Role of THOR, a Conserved Cancer/Testis Long Noncoding RNA. Cell (2017), 171:1559

14. Michelini F, Pitchiaya S, Vitelli V, Sharma S, Gioia U, Pessina F, Cabrini M, Wang Y, Capozzo I, Iannelli F, Matti V, Francia S, Shivashankar GV, Walter NG and d’Adda di Fagagna F#, Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks. Nature Cell Biology (2017), 19:1400. Featured in Storici et al., Nature Cell Biology, 2017 (News & Views)

13. Pitchiaya S, Heinicke LA, Park JI, Cameron E and Walter NG#, Resolving sub-cellular miRNA trafficking and turnover at single-molecule resolution. Cell Reports (2017), 19:630

12. Wang X, Qiao Y, Asangani IA, Ateeq B, Poliakov A, Cieślik M, Pitchiaya S, Chakravarthi BVSK, Cao X, Jing X, Wang CX, Apel IJ, Wang R, Tien JC, Juckette KM, Yan W, Jiang H, Wang S, Varambally S and Chinnaiyan AM#, Development of peptidomimetic inhibitors of the ERG gene fusion product in prostate cancer. Cancer Cell (2017), 31:532

11. Rossiello F, Aguado J, Sepe S, Iannelli F, Nguyen Q, Pitchiaya S, Carninci P and d’Adda di Fagagna F#, DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs. Nature Communications (2017), 8:13980

10. Niknafs YS*, Han S*, Ma T, Speers C, Zhang C, Wilder-Romans K, Iyer MK, Pitchiaya S, Malik R, Hosono Y, Prensner JR, Poliakov A, Singhal U, Xiao L, Kregel S, Siebenaler RF, Zhao SG, Uhl M, Gawronski A, Hayes DF, Pierce LJ, Cao X, Collins C, Backofen R, Sahinalp CS, Rae JM, Chinnaiyan AM# and Feng FY#, The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. Nature Communications (2016), 7:12791

9. Shankar S, Pitchiaya S, Malik R, Kothari V, Hosono Y, Yocum AK, Gundlapalli H, White Y, Firestone A, Cao X, Dhanasekaran SM, Stuckey JA, Bollag G, Shannon K, Walter NG, Kumar-Sinha C and Chinnaiyan AM#, KRAS engages AGO2 to enhance cellular transformation. Cell Reports (2016), 14:1448. Featured in Kiberstis PA, Science, 2016 (Editor’s choice)

8. Nyati S, Schinske-Sebolt K, Pitchiaya S, Chekhovskiy K, Chator A, Chaudhry N, Dosch J, Van Dort ME, Varambally S, Kumar-Sinha C, Nyati MK, Ray D, Walter NG, Yu H, Ross BD and Rehemtulla A#, The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Science Signaling (2015), 8:ra1. Featured in Moustakas et al., Science Signaling, 2015 (Focus) and Barcellos-Hoff MH, Neoplasia, 2015 (Commentary)

7. Bartke RM, Cameron EL, Cristie-David AS, Custer TC, Denies MS, Daher M, Dhakal S, Ghosh S, Heinicke LA, Hoff JD, Hou Q, Kahlscheuer ML, Karslake J, Krieger AG, Li J, Li X, Lund PE, Vo NN, Park J, Pitchiaya S, Rai V, Smith DJ, Suddala KC, Wang J, Widom JR and Walter NG#, Meeting report: SMART timing-principles of single molecule techniques course at the University of Michigan 2014. Biopolymers (2015), 103:296

6. Pitchiaya S*, Heinicke LA*, Custer TC* and Walter NG#, Single molecule fluorescence approaches shed light on intracellular RNAs. Chemical Reviews (2014), 114:3224. Featured in F1000 prime

5. Pitchiaya S, Krishnan V, Custer TC and Walter NG#, Dissecting non-coding RNA mechanisms in cellulo by single molecule high resolution localization and counting. Methods (2013), 63:188

4. Ma J, Liu Z, Michelotti N, Pitchiaya S, Veerapaneni RS, Androsavich JR, Walter NG and Yang W#, High-resolution three-dimensional mapping of mRNA export through the nuclear pore. Nature Communications (2013),  4:2414

3. Pitchiaya S, Androsavich JR and Walter NG#, Intracellular single molecule microscopy reveals two kinetically distinct pathways for microRNA assembly. EMBO reports (2012), 13:709

2. Kuszak AJ, Pitchiaya S, Anand JP, Mosberg HI, Walter NG and Sunahara RK#, Purification and functional reconstitution of monomeric µ-opioid receptors: Allosteric modulation of agonist binding by Gi2. Journal of Biological Chemistry (2009), 284:26732

  1. Pitchiaya S and Krishnan Y#, First blueprint, now bricks: DNA as construction material on the nanoscale. Chemical Society Reviews (2006), 35:1111

Book Chapters

  1. Pitchiaya S*, Androsavich JR* and Walter NG#, Breaking Abbe’s law: Super-accuracy and super-resolution fluorescence microscopy based on single molecule detection. Imaging Life: Biological Systems from Atoms to Tissues (Howard, G.C., Brown, W.E. and Auer, M., Eds.). Oxford University Press(2014), ISBN: 9780195314434