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The Prostate Cancer Foundation announced the recipients of the 2018 PCF Young Investigator Awards. Sethu received this award to unravel molecular heterogeneities in advanced prostate cancer at single cell resolution. To read more about Sethu’s research goal and significance of the study click here.

Genome’s dark matter offers clues to major challenge in prostate cancer Researchers identify a lncRNA that provides insight into a key driver of prostate cancer — and a potential target for future therapy Researchers identified a novel gene they named ARLNC1 that controls signals from the androgen receptor, a key player in prostate cancer. KnockingContinue reading “Our recent paper on ARLNC1 was featured in Science Daily”

How defeating THOR could bring a hammer down on cancer Researchers have uncovered a novel gene they named THOR. It’s a highly conserved long non-coding RNA that plays a role in cancer development. Knocking it out can halt the growth of tumors. This study is published in Cell. Science Daily article Newsweek article

RNA takes over control of DNA break repair Francesca Storici & Ailone E. Tichon, Nature Cell Biology volume 19, pages 1382–1384 (2017) Small RNAs generated at DNA break sites are implicated in mammalian DNA repair. Now, a study shows that following the formation of DNA double-strand breaks, bidirectional transcription events adjacent to the break generateContinue reading “Nature Cell Biology News & Views article on our recent paper on small and long non-coding RNAs at DNA-damage sites”

Sethu was awarded the 2017 NCI Specialized Programs of Research Excellence (SPORE) Career Enhancement Award by The U-M Prostate SPORE launched in 1995 as one of the first NCI-funded SPORE programs in the country. Click here to learn more about the U-M Prostate SPORE.